Superconducting integrated circuits are a leading platform for realizing a utility-scale quantum computer. Continued progress requires a thorough understanding of qubit decoherence, which is largely limited by two-level state (TLS) defects at material interfaces. In this talk, we present a systematic study of energy relaxation in frequency-tunable transmon qubits. We measure spectral and temporal fluctuations of relaxation time in qubits of different geometries, varying both the junction lead shape and the distance between the shunt capacitor electrodes. Our results are consistent with a model where energy relaxation is dominated by defects at the substrate-air interface. With detailed Monte Carlo simulations we are able to localize the dominant defects to within 500 nm of the Josephson junction, where organic residues from fabrication are present. These results motivate a focus on new methods of fabricating junctions that do not involve liftoff.